Genomics Laboratory

The Genomic Laboratory GENYALLab is member of REDLAB, the laboratories network of the Community of Madrid, under the registration number 440. GENYAL LAB participates in ALIBIRD2020-CM project (S2018/BAA-4343): "Therapeutic formulas of precision nutrition for cancer", supported by program call of R & D Activities among Research Groups of the Community of Madrid (Technologies 2018) and co-financed with European Union Structural Funds.

                                                     

                               


The Genomics Laboratory has the necessary infrastructure for providing genetic and genomic services, as well as metabolomic analysis, providing technical and scientific support to researchers and private companies.

This Laboratory is equiped with appropriate devices for sample processing and nucleic acid extraction and quantification, as well as the latest hardware for gene expression and high performance genotyping analysis, such as the latest generation QuantStudio™ 12K Flex System apparatus. Other equipments for genomic analysis include qPCR 7900HT and conventional PCRs.

These devices have different applications, such as digital PCR, DNA fragment analysis, expression/gene quantification analysis, allele discrimination using TaqMan probes, and the detection of SNPs and mutations, etc.

In addition, the laboratory has specific equipment for analyzing metabolites with different techniques such as chromatography (Agilent 1260 HPLC system), cellular metabolism measurement (Seahorse XFe96), or simultaneous detection and quantitation of several secreted proteins (Luminex MAGPIX® System). These techniques provide a high value added tool in nutrigenomic and nutrigenetic studies, to achieve effective Precision Nutrition.

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Dr. Susana Molina Arranz

Lab Manager and Technical responsible of the Genomic Laboratory

Susana Molina Arranz, performed her PhD studies in the group of Prof. Luis Carrasco at the “Centro de Biología Molecular Severo Ochoa” (CSIC-UAM). In 2007 she joined Dr. Juan M. Torres group at “Centro de Investigación en Sa- nidad Animal” (INIA), a research group about prion diseases and its strain barriers. Between 2008 and 2009 she joined the group of Fernando Valdivieso at the “Centro de Biología Molecular Severo Ochoa” (CSIC-UAM), working as a technician generating biological tools for the therapeutic investigation of Alzheimer Disease. During all these years she acquired experience in cell culture, as well as different techniques in molecular biology as western blotting, cloning, and nucleic acid and protein purifications. In 2009 started in IMDEA Food as the Technical responsible of the Genomic Laboratory, working both in the investigation line about nutritional genomics of cancer, as well as in GENYAL Nutrigenomic Laboratory. Her work in the GENYAL Platform includes processing and analyzing samples from the different intervention studies that are developing in IMDEA Food, but also from external companies and research centers interested in genotyping studies.

Email: susana.molina@imdea.org
Phone: +34 91 727 81 00, ext. 508 




Members

Mónica Gómez Patiño                                                              Beatriz Martínez Blanco                          Dr. Carmen Crespo Lorenzo                                    
Biosafety and occupational risk prevention Manager           Laboratory Technician                                Technician Doctor of the laboratory                                                                      Senior Lab Technician                                                  
                                                                               

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Mónica Gómez Patiño

Biosafety and occupational risk prevention Manager. Senior Lab Technician 

Monica Gómez Patiño is Expert in Biosafety in laboratories and is a Senior Lab Technician
Specialist in Chemical and Microbiological Analysis. In addition, she holds a certificate
of higher education in Instrumental Analysis Techniques. She has professional experience in the field of pharmaceutics working in private companies gaining experience in the field of biochemistry by applying a wide range of techniques to identify, quantify and detect specific proteins. Moreover, she worked in Public Research Organizations such as INIA, CIB-CSIC acquiring wide experience in Chromatographic techniques and in Genomic and Molecular biology area. Now, in IMDEA Food Institute, she is the Head of the Biosecurity and Biohazardous, Chemical and Cytotoxic waste Management and supports the management of the laboratories. She is also responsible of the Biosafety Laboratory Level P2, processes and manages the international Import and Export of biological samples and is in charge of managing the official accreditations and permits for the laboratories and she is the Responsible of the Occupational Risks Prevention. Finally, she is a senior Scientific Technician at the GENYAL Platform applying both genomic and lipidomic techniques in human samples and she works a Scientific Technician in the Group of Molecular and Nutritional Genomics of Cancer leaded by Dr. Ana Ramírez de Molina where she collaborates with researchers in several projects.

Email: monica.gomez@imdea.org
Phone: +34 91 727 81 00 ext. 505

Beatriz Martínez Blanco

Laboratory technician

Beatriz Martínez Blanco obtained her advanced training as a Quality Control Technician in 2006. In 2010, she obtained her diploma related with the Discovery of New Drugs using the HTS technique at the Juan Carlos University in association with GlaxoSmith- Kline Basic Research Center. During the period 2007-2009 she worked as a Quality Control Inspector at Lilly. During the period between 2010 and 2015, she worked as a Laboratory Manager at the Parque Cientifico of Madrid, in collaboration with Antonio Díaz and Alejandro Arranz. In 2016, she joined CBMSOCSIC Center as a Microbiology Laboratory Technician under the supervision of Mercedes Dávila. In 2017 she had the opportunity to work as Industrial Developer Technician at Rovi Research Center. During her career path, Beatriz had acquired deep knowledge in GLP, GMP, ISO rules, being part of 6 Sigma projects and working in audit programs. She also has experience in analytical and molecular biology techniques. She joined IMDEA Food in 2017 as a Laboratory Technician for the GENYAL Platform.

Email: beatriz.martinez@imdea.org
Phone: +34 91 727 81 00

Dr. Carmen Crespo Lorenzo

Technician Doctor of the laboratory

Mª del Carmen Crespo Lorenzo has a first degree in Molecular and Cellular Biology from the IE University of Segovia (2010). In 2013 she obtained a Master degree in Pharmacological Research from the Universidad Autónoma de Madrid (UAM). As part of her research activity, she joined the research project team “Genetic and genomic analysis in patients affected by Gorham-Stout Disease and General Lymphatic Anomalies” at the Hospital Universitario La Paz (Supervisor: Dr. Pablo Lapunzina). In June 2014, she started her Ph.D. program at IMDEA’s Bioactive Ingredients Food Group (Supervisors: Prof. Francesco Visioli and Dr. Alberto Dávalos). Her thesis is focused on the protective function of specific micronutrients (soy isoflavones, hydroxytyrosol, and bioactive polar lipids) performing in vitro, in vivo and placebo-controlled, randomized trials in healthy volunteers to evaluate the possible beneficial effect that these molecules play on cardiovascular and neurodegenerative diseases. Currently, her research focuses on bioactive polar lipids, as part of a nutritional supplement, studying whether these compounds contribute to the improvement or delaying of mild cognitive impairment and collaborates as a laboratory technician of the Platform GENYAL (Genomics and Nutrition). Her publication record shows 15 papers.

Email: carmen.crespo@imdea.org
Phone: +34 91 727 81 00, ext. 508