Research projects > International Consortia


Application of new technologies and methods in nutrition research the example of phenotypic flexibility (GA289511)

Principal investigator: Dr. José María Ordovás Muñoz
Funded by: Comisión Europea. VII programa Marco I+D
Duration: 2012 - 2016

A total of 23 research groups are involved in the Nutritech project. These groups from a variety of European and American leader institutions in the research field of Nutritional Genomics. Using technical and analytical methodologies, Nutritech will evaluate the gen-nutrient relationship. The included technologies are the most novel biological technologies.

They refer to omics technologies such as genomic, transcriptomic, proteomic and metabolomics, among others. The application of all these technologies to the nutritional genomics research will allow revealing the dietary modulation of genes from different perspectives to define how the effect of the diet on genes expands to proteins and metabolites. 


Interindividual variation in response to consumption of plant food bioactives and determinants
involved (FA 1403)

Principal investigator: Dr. José María Ordovás Muñoz
Funded by: European Comission
Duration: 2014 - 2018

To combat the burden of cardiometabolic disease, which constitutes a major public health issue in Europe, it is of crucial importance to develop efficient strategies that target the dietary behaviours of European consumers and improve the food supply.

Plant foods are rich sources of a large range of bioactive compounds that beneficially affect our health, particularly by decreasing the risk of cardiometabolic diseases. POSITIVe specifically addresses inter-individual variation in bioavailability and physiological responses to consumption of plant food bioactives in relation to cardiometabolic endpoints.


Anti-inflammatory and healing activity of sea cucumber (Isostichopus badionotus) in a murine model: characterization of pharmacological activity and cellular mechanisms involved (CB.2013-01 No. 22173)

Principal investigator: Dr. Alberto Dávalos Herrera
Funded by: CONACYT Consejo Nacional de Ciencia y Tecnología (Mexico)
Duration: 2015 - 2018

Uncontrolled inflammatory response is a major driver of many modern human chronic diseases. The natural world has been the source of novel anti-inflammatory and other biologically-active agents.

Plants, insects and marine organisms, including algae and invertebrate marine organisms, have been screened for the presence of anti-inflammatory agents. Sea cucumbers are marine invertebrates, considered by the traditional Chinese medicine as tonic foods, attributing them with a wide range of biological effects, including anti-inflammatory. However, their mechanism of action is poorly described.

Isostichopus badionotus, is a sea cucumber from the Peninsula of Yucatan (Mexico) whose many biological activities are not well characterized. “inflammarine” aims to contribute to a better understanding of the anti-inflammatory activity and mechanisms of action of the bioactive components of sea cucumber I. badionotus.

Our results will allow the development of possible therapies from this marine invertebrate and support the search for therapeutic alternatives to combat the devastating consequences of the
chronic inflammatory processes that today afflict our modern society.