Publications

Previous years

2016

During 2016, the institute has published 82 articles in magazines of high international impact. 72% of the published articles are in the first quartile of the SCI (Science Citation Index), which is indicative of the scientific excellence of the Institute.

1. Irvin MR, Rotroff DM, Aslibekyan S, Zhi D, Hidalgo B, Motsinger-Reif A, Marvel S, Srinivasasainagendra V, Claas SA, Buse JB, Straka RJ, Ordovas JM, Borecki IB, Guo X, Chen IY, Rotter JI, Wagner MJ, Arnett DK. A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies. Pharmacogenet
Genomics. 2016 Jul;26(7):324-33. doi: 10.1097/FPC.0000000000000219 


2. Bigornia SJ, Harris WS, Falcón LM, Ordovás JM, Lai CQ, Tucker KL. The Omega-3 Index Is Inversely Associated with Depressive Symptoms among Individuals with Elevated Oxidative Stress Biomarkers. Journal of Nutrition 2016 Apr;146(4):758-66. doi: 10.3945/ jn.115.222562


3. Talavera-Garcia E, Delgado-Lista J, Garcia-Rios A, Delgado-Casado N, Gomez-Luna P, Gomez-Garduño A, Gomez-Delgado F, Alcala-Diaz JF, Yubero-Serrano E, Marin C, Perez-Caballero AI, Fuentes-Jimenez FJ, Camargo A, Rodriguez-Cantalejo F, Tinahones FJ, Ordovas JM, Perez-Jimenez F, Perez-Martinez P, Lopez-Miranda J.Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study). PLoS One. 2016 Apr 11;11(4):e0153096. doi: 10.1371/journal.pone.0153096. eCollection 2016. Erratum in: PLoS One. 2016, 11(6):e0157213


4. Corella D, Asensio EM, Coltell O, Sorlí JV, Estruch R, Martínez-González MÁ, Salas-Salvadó J, Castañer O, Arós F, Lapetra J, Serra-Majem L, Gómez-Gracia E, Ortega-Azorín C, Fiol M, Espino JD, Díaz-López A, Fitó M, Ros E, Ordovás JM. CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic  ubjects: dietary modulation in the PREDIMED randomized trial. Cardiovascular Diabetology. 2016 Jan;15(4). doi: 10.1186/s12933-015-0327-8


5. Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Sami ri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YD, Hernandez DG, Borecki I, Chasman DI, Rich SS, Ferrucci L, Irvin MR, Aslibekyan S, Zhi D, Tiwari HK, Claas SA, Sha J, Kabagambe EK, Lai CQ, Parnell LD, Lee YC, Amouyel P, Lambert JC, Psaty BM, King IB, Mozaffarian D, McKnight B, Bandinelli S, Tsai MY, Ridker PM, Ding J, Mstat KL, Liu Y, Sotoodehnia N, Barberger-Gateau P, Steffen LM, Siscovick DS, Absher D, Arnett DK, Ordovás JM, Lemaitre RN. Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and
Aging Research in Genomic Epidemiology consortium. American Journal of Clinical Nutrition. 2016 Feb;103(2):567-78. doi: 10.3945/ajcn.115.112987. 2016 r e p o r t. 73


6. Das M, Sha J, Hidalgo B, Aslibekyan S, Do AN, Zhi D, Sun D, Zhang T, Li S, Chen W, Srinivasan SR, Tiwari HK, Absher D, Ordovas JM, Berenson GS, Arnett DK, Irvin MR. Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study. PLoS One. 2016 Jan 25;11(1):e0145789. doi: 10.1371/journal.pone.014578910.3305/nh.2015.31.sup3.8765


7. Ferguson JF, Allayee H, Gerszten RE, Ideraabdullah F, Kris-Etherton PM, Ordovás JM, Rimm EB, Wang TJ, Bennett BJ. Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association. Circulation Cardiovascular Genetics Journal. 2016 Jun;9(3):291-313. doi: 10.1161/HCG.0000000000000030


8. Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, Alcala-Diaz JF, Perez-Caballero AI, Gomez-Delgado F, Fuentes F, Quintana-Navarro G, Lopez-Segura F, Ortiz-Morales AM, Delgado-Casado N, Yubero-Serrano EM, Camargo A, Marin C, Rodriguez-Cantalejo F, Gomez-Luna P, Ordovas JM, Lopez-Miranda J, Perez-Jimenez F. CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (the CORDIOPREV study): Rationale, methods, and baseline characteristics: A clinical trial comparing the efficacy of a Mediterranean diet rich in olive oil versus a low-fat diet on cardiovascular disease in coronary patients. American Heart Journal. 2016 Jul;177:42-50. doi: 10.1016/j.ahj.2016.04.011


9. Dashti HS, Zuurbier LA, de Jonge E, Voortman T, Jacques PF, Lamon-Fava S, Scheer FA, Kiefte-De Jong JC, Hofman A, Ordovás JM, Franco OH, Tiemeier H. Actigraphic sleep fragmentation, efficiency and duration associate with dietary intake in the Rotterdam Study. Journal of Sleep Research. 2016 Aug;25(4):404-11. doi: 10.1111/jsr.12397


10. Laclaustra M, Casasnovas JA, Fernandez-Ortiz A, Fuster V, Leon-Latre M, Jimenez-Borreguero LJ, Pocovi M, Hurtado-Roca Y, Ordovas JM, Jarauta E, Guallar E, Ibanez B, Civeira, F. Femoral and Carotid Subclinical Atherosclerosis Association With Risk Factors and Coronary Calcium The AWHS Study. Journal of the American College of Cardiology. 2016 Mar;67(11):1263-1274. doi: 10.1016/j.jacc.2015.12.056


11. Mico V, Martin R, Lasuncion MA, Ordovas JM, Daimiel L. Unsuccessful Detection of Plant MicroRNAs in Beer, Extra Virgin Olive Oil and Human Plasma After an Acute Ingestion of Extra Virgin Olive Oil. Plant Foods for Human Nutrition. 2016 Mar;71(1):102-108. doi: 10.1007/s11130-016-0534-9 

12. Johnston JD, Ordovas JM, Scheer Frank A, Turek FW. Circadian Rhythms, Metabolism, and Chrononutrition in Rodents and Humans. Advances in Nutrition. 2016 Mar 15;7(2):399-406. doi:10.3945/an.115.010777


13. Micó V, Díez-Ricote L, Daimiel L. Nutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health. International Journal of Molecular Sciences. 2016 Feb;17(3):299. doi: 10.3390/ijms17030299
food. 74


14. Nobrega-Pereira S, Fernandez-Marcos PJ, Brioche T, Gomez-Cabrera MC, Salvador- Pascual A, Flores JM, Vina J, Serrano M. G6PD protects from oxidative damage and improves healthspan in mice. Nature Communications. 2016 Mar 15;7:10894. doi: 10.1038/ncomms10894


15. Ambrogio C, Gomez-Lopez G, Falcone M, Vidal A, Nadal E, Crosetto N, Blasco RB, Fernandez-Marcos PJ, Sanchez-Cespedes M, Ren XM, Wang Z, Ding K, Hidalgo M, Serrano M, Villanueva A, Santamaria D, Barbacid M. Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma. Nature Medicine. 2016 March;22(3):270-277. doi: 10.1038/nm.4041


16. Fernandez-Marcos PJ, Serrano M. Mitochondrial Damage Induces Senescence with a Twisted Arm. Cell Metabolism. 2016 Feb;23(2):229-30. doi:10.1016/j.cmet.2016.01.012

17. Gil-Ramirez A, Caz V, Smiderle FR, Martin-Hernandez R, Largo C, Tabernero M, Marin FR, Iacomin M, Reglero G, Soler-Rivas C. Water-Soluble Compounds from Lentinula edodes
Influencing the HMG-CoA Reductase Activity and the Expression of Genes Involved in the Cholesterol Metabolism. Journal of Agricultural and Food Chemistry. 2016 Feb;64(9):1910-1920. doi: 10.1021/acs.jafc.5b05571


18. Caz V, Gil-Ramirez A, Santamaria M, Tabernero M, Soler-Rivas C, Martin-Hernandez R, Marin FR, Reglero G, Largo, C. Plasma Cholesterol-Lowering Activity of Lard Functionalized with Mushroom Extracts Is Independent of Niemann-Pick C1-like 1 Protein and ABC Sterol Transporter Gene Expression in Hypercholesterolemic Mice. Journal of Agricultural and Food Chemistry. 2016 Feb;64(8):1686-1694. doi: 10.1021/acs.jafc.5b05490

19. Lopez-Padilla A, Ruiz-Rodriguez A, Reglero G, Fornari T. Study of the diffusion coefficient of solute-type extracts in supercritical carbon dioxide: Volatile oils, fatty acids and fixed oils. Journal of Supercritical Fluids. 2016 Mar;109:148-156. doi: 10.1016/j.supflu.2015.11.017


20. Vázquez L, Jordán A, Reglero G, Torres CF. A First Attempt into the Production of Acylglycerol Mixtures from Echium Oil. Frontiers in Bioengineering and Biotechnology. 2016 Jan 19; 3:208. doi: 10.3389/fbioe.2015.00208


21. Bermejo, DV , Ibanez, E , Reglero, G , Fornari, T. Effect of cosolvents (ethyl lactate, ethyl acetate and ethanol) on the supercritical CO2 extraction of caffeine from green tea. Journal of Supercritical Fluids, 2016 Jan;107:507-512. doi:  0.1016/j.supflu.2015.07.008 


22. Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdman  J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen 2016 r e p o r t. 75 A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ, CHD Exome+ Consortium, CARDIoGRAM Exome Consortium, Global Lipids Genetics Consortium. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science. 2016 Mar;351(6278):1166-71. doi: 10.1126/science.aad3517


23. Baena M, Sangüesa G, Dávalos A, Latasa MJ, Sala-Vila A, Sánchez RM, Roglans N, Laguna JC, Alegret M. Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues. Scientific Reports - Nature. 2016 May;6:26149. doi: 10.1038/srep26149


24. Díez-Planelles C, Sánchez-Lozano P, Crespo MC, Gil-Zamorano J, Ribacoba R, González N, Suárez E, Martínez-Descals A, Martínez-Camblor P, Álvarez V, Martín-Hernández R, Huerta-Ruíz I, González-García I, Cosgaya JM, Visioli F, Dávalos A, Iglesias-Gutiérrez E, Tomás-Zapico C. Circulating microRNAs in Huntington’s disease: Emerging mediators in
metabolic impairment. Pharmacological Research. 2016 May;108:102-110. doi: 10.1016/j. phrs.2016.05.005


25. Parri A, Fitó M, Torres CF, Muñoz-Aguayo D, Schröder H, Cano JF, Vázquez L, Reglero G, Covas MI. Alkylglycerols reduce serum complement and plasma vascular endothelial growth factor in obese individuals. Inflammopharmacology. 2016 Jun; 24(2-3):127-31. doi: 10.1007/s10787-016-0265-4


26. Ferguson LR, De Caterina R, Görman U, Allayee H, Kohlmeier M, Prasad C, Choi MS, Curi R, de Luis DA, Gil Á, Kang JX, Martin RL, Milagro FI, Nicoletti CF, Nonino CB, Ordovas JM, Parslow VR, Portillo MP, Santos JL, Serhan CN, Simopoulos AP, Velázquez-Arellano,A, Zulet MA, Martinez JA. Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition. Journal of Nutrigenetics and Nutrigenomics. 2016 May;9(1):12-27. doi: 10.1159/000445350 


27. Burgos-Ramos E, Canelles S, Frago LM, Chowen JA, Arilla-Ferreiro E, Argente J, Barrios V. Improvement in glycemia after glucose or insulin overload in leptin-infused rats is associated with insulin-related activation of hepatic glucose metabolism. Nutrition and Metabolism (Lond). 2016 Mar 1;13:19. doi: 10.1186/s12986-016-0079-9. eCollection 2016


28. Bacchetta L, Visioli F, Cappelli G, Caruso E, Martin G, Nemeth E, Bacchetta G, Bedini G, Wezel A, van Asseldonk T, van Raamsdonk L, Mariani F, On Behalf Of The Eatwild Consortium. A manifesto for the valorization of wild edible plants. Journal of Ethnopharmacology. 2016 Sep 15;191:180-7. doi: 10.1016/j.jep.2016.05.061 food, 76


29. Tomé-Carneiro J, Crespo MC, Iglesias-Gutierrez E, Martín R, Gil-Zamorano J, Tomas-Zapico C, Burgos-Ramos E, Correa C, Gómez-Coronado D, Lasunción MA, Herrera E, Visioli F, Dávalos A. Hydroxytyrosol supplementation modulates the expression of miRNAs in rodents and in humans. The Journal of Nutritional Biochemistry. 2016 May;31,34:146-155. doi: 10.1016/j.jnutbio.2016.05.009


30. Mendiola M, Martínez-Marin V, Herranz J, Heredia V, Yébenes L, Zamora P, Castelo B, Pinto Á, Miguel M, Díaz E, Gámez A, Fresno JÁ, Ramirez de Molina A, Hardisson D, Espinosa E, Redondo A. Predictive value of angiogenesis-related gene profiling in patients with HER2-negative metastatic breast cancer treated with bevacizumab and weekly paclitaxel. Oncotarget. 2016 Apr;7(17):24217-27. doi: 10.18632/oncotarget.8128 


31. Baquedano E, Burgos-Ramos E, Canelles S, González-Rodríguez A, Chowen JA , Argente J, Barrios V, Valverde AM and Frago LM. Increased oxidative stress and apoptosis in the hypothalamus ofdiabetic male mice in the insulin receptor substrate-2 knockout model. Disease Models & Mechanism. 2016 May;9(5):573-83. doi: 10.1242/dmm.023515


32. Sayols-Baixeras S, Subirana I, Lluis-Ganella C, Civeira F, Roquer J, Do AN, Absher D, Cenarro A, Muñoz D, Soriano-Tárraga C, Jiménez-Conde J, Ordovas JM, Senti M, Aslibekyan S, Marrugat J, Arnett DK, Elosua R. Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study. Human Molecular Genetics. 2016 Sep. pii: ddw285. [Epub ahead of print]


33. Garaulet M, Vera B, Bonnet-Rubio G, Gómez-Abellán P, Lee YC, Ordovás JM. Lunch eating predicts weight-loss effectiveness in carriers of the common allele at PERILIPIN1: the ONTIME (Obesity, Nutrigenetics, Timing, Mediterranean) study. American Journal of Clinical Nutrition. 2016 Oct;104(4):1160-1166. Epub 2016 Sep 14


34. Noel SE, Arevalo S, Smith CE, Lai CQ, Dawson-Hughes B, Ordovas JM, Tucker KL. Genetic admixture and body composition in Puerto Rican adults from the Boston Puerto Rican Osteoporosis Study. Journal of Bone and Mineral Metabolism. 2016 Sep. [Epub ahead of print]


35. Smith CE, Coltell O, Sorlí JV, Estruch R, Martínez-González MÁ, Salas-Salvadó J, Fitó M, Arós F, Dashti HS, Lai CQ, Miró L, Serra-Majem L, Gómez-Gracia E, Fiol M, Ros E, Aslibekyan S, Hidalgo B, Neuhouser ML, Di C, Tucker KL, Arnett DK, Ordovás JM, Corella D. Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. Scientific
Reports - Nature. 2016 Sep;6:33188. doi: 10.1038/srep33188 


36. Peñalvo JL, Fernández-Friera L, López-Melgar B, Uzhova I, Oliva B, Fernández-Alvira JM, Laclaustra M, Pocock S, Mocoroa A, Mendiguren JM, Sanz G, Guallar E, Bansilal S, Vedanthan R, Jiménez-Borreguero LJ, Ibañez B, Ordovás JM, Fernández-Ortiz A, Bueno H, Fuster V. Association Between a Social-Business Eating Pattern and Early Asymptomatic Atherosclerosis. Journal of the American College of Cardiology. 2016 Aug;68(8):805-14. doi: 10.1016/j.jacc.2016.05.080, 2016 r e p o r t, 77


37. Barragán R, Coltell O, Asensio EM, Francés F, Sorlí JV, Estruch R, Salas-Huetos A, Ordovas JM, Corella D. MicroRNAs and Drinking: Association between the Pre-miR- 27a rs895819 Polymorphism and Alcohol Consumption in a Mediterranean Population. International Journal of Molecular Sciences. 2016;17(8). pii: E1338. doi: 10.3390/
ijms17081338


38. Smith CE, Fullerton SM, Dookeran KA, Hampel H, Tin A, Maruthur NM, Schisler JC, Henderson JA, Tucker KL, Ordovás JM. Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities. Health Affairs. (Millwood). 2016;35(8):1367-73. doi: 10.1377/hlthaff.2015.1476


39. Rangel-Zúñiga OA, Corina A, Lucena-Porras B, Cruz-Teno C, Gómez-Delgado F, Jiménez- Lucena R, Alcalá-Díaz JF, Haro-Mariscal C, Yubero-Serrano EM, Delgado-Lista J, López-Moreno J, Rodríguez-Cantalejo F, Camargo A, Tinahones FJ, Ordovás JM, López-Miranda J, Pérez-Martínez P. TNFA gene variants related to the inflammatory status and its
association with cellular aging: From the CORDIOPREV study. Experimental Gerontology. 2016;83: 56-62. doi: 10.1016/j.exger.2016.07.015


40. Yubero-Serrano EM, Delgado-Lista J, Alcala-Diaz JF, Garcia-Rios A, Perez-Caballero AI, Blanco-Rojo R, Gomez-Delgado F, Marin C, Tinahones FJ, Caballero J, Ordovas JM, van Ommen B, Perez-Jimenez F, Perez-Martinez P, Lopez-Miranda J. A dysregulation of glucose metabolism control is associated with carotid atherosclerosis in patients with coronary  heart disease (CORDIOPREV-DIAB study). Atherosclerosis. 2016;253:178-185 .pii: S0021-9150(16)31204-7. doi: 10.1016/j.atherosclerosis.2016.07.903


41. Blanco-Rojo R, Delgado-Lista J, Lee YC, Lai CQ, Perez-Martinez P, Rangel-Zuñiga O, Smith CE, Hidalgo B, Alcala-Diaz JF, Gomez-Delgado F, Parnell LD, Arnett DK, Tucker KL, Lopez-Miranda J, Ordovas JM. Interaction of an S100A9 gene variant with saturated fat and carbohydrates to modulate insulin resistance in 3 populations of different ancestries. The
American Journal of Clinical Nutrition. 2016;104(2):508-17. doi: 10.3945/ajcn.116.130898, food, 78


42. Xin XX, Chen Y, Chen D, Xiao F, Parnell LD, Zhao J, Liu L, Ordovas JM, Lai CQ, Shen LR. Supplementation with Major Royal-Jelly Proteins Increases Lifespan, Feeding, and Fecundity in Drosophila. Journal of Agricultural and Food Chemistry. 2016; 64(29):5803-12. doi: 10.1021/acs.jafc.6b00514


43. Fernandez-Marcos PJ, Nóbrega-Pereira S. NADPH: new oxygen for the ROS theory of aging. Oncotarget. 2016 Aug;7(32):50814-50815. doi: 10.18632/oncotarget.10744


44. Margot H, Zwietering MH, Joosten H, Stephan R. Determination of single cell lag times of Cronobacter spp. strains exposed to different stress conditions: Impact on detection. International Journal of Food Microbiology. 2016 Nov;236:161-6. doi: 10.1016/j.ijfoodmicro. 2016.08.002


45. Margot H, Tasara T, Zwietering MH, Joosten H, Stephan R. Effects of different media on the enrichment of low numbers of Shiga toxin-producing Escherichia coli in mung bean sprouts and on the development of the sprout microbiome. International Journal of Food. Microbiology. 2016 Sep;232:26-34. doi: 10.1016/j.ijfoodmicro.2016.05.005 


46. Hernando B, Ibarrola-Villava M, Fernandez LP, Peña-Chilet M, Llorca-Cardeñosa M, Oltra SS, Alonso S, Boyano MD, Martinez-Cadenas C, Ribas G. Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin. Biology of Sex Differences. 2016 Mar;7:17. doi: 10.1186/s13293-016-0070-1. eCollection 2016


47. Fernández-Suárez ME, Escolà-Gil JC, Pastor O, Dávalos A, Blanco-Vaca F, Lasunción MA, Martínez-Botas J, Gómez-Coronado D. Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport. Scientific Reports - Nature. 2016 Sep; 6:32105. doi: 10.1038/srep32105, 2016 r e p o r t
79


48. Lopez-Padilla A, Ruiz-Rodriguez A, Florez CER, Barrios DMR, Reglero G, Fornari T. Vaccinium meridionale Swartz Supercritical CO2 Extraction: Effect of Process Conditions and Scaling Up. Materials. 2016 Jul;(7) 519. doi:10.3390/ma9070519 


49. Tome-Carneiro J, Visioli F. Polyphenol-based nutraceuticals for the prevention and treatment of cardiovascular disease: Review of human evidence. Phytomedicine. 2016 Oct;(23)11:1145-1174. doi: 10.1016/j.phymed.2015.10.018


50. Corzo-Martínez M, Vázquez L, Arranz-Martínez P, Menéndez N, Reglero G, Torres C. Production of a Bioactive Lipid-based Delivery System from Ratfish Liver Oil by Enzymatic Glycerolysis. Food and Bioproducts Processing. In Press, Accepted Manuscript; 2016 Aug;100:311-322. Subdivisión: A. doi: 10.1016/j.fbp.2016.08.003


51. de la Iglesia R, Loria-Kohen V, Zulet MA, Martinez JA, Reglero G, Ramirez-de Molina A. Dietary strategies implicated in the prevention and treatment of metabolic síndrome. International Journal of Molecular Sciences. 2016 Nov;17(11). pii: E1877. doi: 10.3390/ijms17111877


52. Perez-Martinez P, Alcala-Diaz JF, Kabagambe EK, Garcia-Rios A, Tsai MY, Delgado-Lista J, Kolovou G, Straka RJ, Gomez-Delgado F, Hopkins PN, Marin C, Borecki I, Yubero-Serrano EM, Hixson JE, Camargo A, Province MA, Lopez Moreno J, Rodriguez-Cantalejo F, Tinahones FJ, Mikhailidis DP, Perez-Jimenez F, Arnett DK, Ordovas JM, Lopez-Miranda J. Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary
heart disease patients. Journal of Clinical Lipidology. 2016 Sep-Oct;10(5): 1163-1171. doi: 10.1016/j.jacl.2016.05.009


53. Correia NC, Melão A, Póvoa V, Sarmento L, Gómez de Cedrón M, Malumbres M, Enguita FJ, Barata JT. MicroRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia. Oncotarget. 2016 Feb;7(7):8268-8281. doi: 10.18632/oncotarget.6987


54. Day, K ; Waite, LL ; Alonso, A ; Irvin, MR ; Zhi, D ; Thibeault, KS ; Aslibekyan, S ; Hidalgo, B ; Borecki, IB ; Ordovas, JM ; Arnett, DK ; Tiwari, HK ; Absher, DM. Heritable DNA Methylation in CD4(+) Cells among Complex Families Displays Genetic and Non-Genetic Effects. Plos One. 2016 Oct;11(10). doi: 10.1371/journal.pone.0165488


55. Corella, D; Coltell, O; Sorli, JV; Estruch, R; Quiles, L; Martinez-Gonzalez, MA; Salas-Salvado, J; Castaner, O; Aros, F; Ortega-Calvo, M; Serra-Majem, L  Gomez-Gracia, E; Portoles, O; Fiol, M; Espino, JD; Basora, J; Fito, M; Ros, E; Ordovas, JM. Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores. Nutrients. 2016 Dec;8(12):793. doi: 10.3390/nu8120793, food 80


56. Martin, D; del Hierro, JN; Bermejo, D; Fernandez-Ruiz, R; Fornari, T; Reglero, G. Bioaccessibility and Antioxidant Activity of Calendula officinalis Supercritical Extract as Affected by in Vitro Codigestion with Olive Oil. Journal Of Agricultural and Food Chemistry. 2016 Nov;64(46):8828-8837. doi: 10.1021/acs.jafc.6b04313


57. Lopez-Guadamillas, E; Fernandez-Marcos, PJ; Pantoja, C; Munoz-Martin, M; Martine z, D; Gomez-Lopez, G; Campos-Olivas, R; Valverde, AM; Serrano, M. p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPAR alpha. Scientific Reports - Nature. 2016 Oct;6:34542. doi: 10.1038/srep34542

58. Mosteiro, L; Pantoja, C; Alcazar, N; Marion, RM; Chondronasiou, D; Rovira, M; Fernandez-Marcos, PJ; Munoz-Martin, M; Blanco-Aparicio, C; Pastor, J; Gomez-Lopez, G; De Martino, A; Blasco, MA; Abad, M; Serrano, M. Tissue damage and senescence provide critical signals for cellular reprogramming in vivo. Science. 2016 Nov;354(6315). pii: aaf4445. doi: 10.1126/science.aaf4445


59. Lopez-Guadamillas, E; Munoz-Martin, M; Martinez, S; Pastor, J; Fernandez-Marcos, PJ; Serrano, M. PI3K alpha inhibition reduces obesity in mice. Aging-US. 2016 Nov;8(11):2747-2753. doi: 10.18632/aging.101075


60. Cejas, Paloma; Cavazza, Alessia; Yandava, Chandri; Moreno, Victor; Horst, David; Moreno-Rubio, Juan; Burgos, Emilio; Mendiola, Marta; Taing, Len; Goel, Ajay; Feliu, Jaime; Shivdasani, Ramesh A. Transcriptional regulator CNOT3 defines an aggressive colorectal cancer subtype. Cancer Research. Epub 2016 Nov 29. doi: 10.1158/0008-5472.CAN-16-1346


61. Lopez-Gomez, M; Casado, E; Munoz, M; Alcala, S; Moreno-Rubio, J; D’Errico, G; Jimenez- Gordo, AM; Salinas, S; Sainz, B. Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectives. Critical Reviews in Oncology Hematology.  2016 Nov;107:54-71. doi: 10.1016/j.critrevonc.2016.08.006


62. Vargas T, Moreno-Rubio J, Herranz J, Cejas P, Molina S, Mendiola M, Burgos E, Custodio AB, De Miguel M, Martín-Hernández R, Reglero G, Feliu J, Ramírez de Molina A. 3’UTR Polymorphism in ACSL1 Gene Correlates with Expression Levels and Poor Clinical Outcome in Colon Cancer Patients. PLoS One. 2016 Dec 19;11(12):E0168423. doi: 10.1371/journal. pone.0168423. eCollection 2016


63. Gomez-Delgado F, Delgado-Lista J, Lopez-Moreno J, Rangel-Zuñiga OA, Alcala-Diaz JF, Leon-Acuña A, Corina A, Yubero-Serrano E, Torres-Peña JD, Camargo A, Garcia-Rios A, Caballero J, Castaño J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Telomerase RNA Component Genetic Variants Interact With the Mediterranean Diet Modifying the Inflammatory Status and its Relationship With Aging: CORDIOPREV Study; The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2016 Oct; pii: glw194; doi: 10.1093/gerona/glw194, 2016 r e p o r t,81


64. Visioli F, Artaria C. Astaxanthin in cardiovascular health and disease: mechanisms ofaction, therapeutic merits, and knowledge gaps. Food & Function. 2016 Dec Epub ahead
of print. doi: 10.1039/c6fo01721e


65. García-Blanco T, Dávalos A, Visioli F. Tea, cocoa, coffee, and affective disorders: vicious or virtuous cycle?. Journal of Affective Disorders. 2016 Nov Epub ahead of print. pii: S0165- 0327(16)30783-2. doi: 10.1016/j.jad.2016.11.033


66. Cejas, P; Li, L; O’Neill, NK; Duarte, M; Rao, P; Bowden, M; Zhou, CSW; Mendiola, M; Burgos, E; Feliu, J; Moreno-Rubio, J; Guadalajara, H; Moreno, V; Garcia-Olmo, D; Bellmunt, J; Mullane, S; Hirsch, M; Sweeney, CJ; Richardson, A; Liu, XS; Brown, M; Shivdasani, RA; Long, HW. Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific
enhancer profiles. Nature Medicine. 2016 Jun;22(6):685-91. doi: 10.1038/nm.4085


67. de la Iglesia R, Espinosa-Salinas I, Aguilar-Aguilar E, Marcos-Pasero H, Reglero G, Ramírez De Molina A, Loria-Kohen V. Consumo de complementos dietéticos y cambios alimentarios en la menopausia. Revista Española de Nutrición Comunitaria. 2016 Oct Vol 22. Sup 1.


68. Loria-Kohen, V; Espinosa-Salinas, I; Marcos-Pasero, H; Lourenco-Nogueira, T; Herranz, J; Molina, S; Reglero, G; de Molina, AR. Polymorphism in the CLOCK gene may influence the effect of fat intake reduction on weight loss. Nutrition. 2016 Apr;32(4):453-460. doi: 10.1016/j.nut.2015.10.013


69. Gil-Ramirez, A; Caz, V; Martin-Hernandez, R; Marin, FR; Largo, C; Rodriguez-Casado, A; Tabernero, M; Ruiz-Rodriguez, A; Reglero, G; Soler-Rivas, C. Modulation of cholesterol-related gene expression by ergosterol and ergosterol-enriched extracts obtained from Agaricus bisporus. European Journal of Nutrition. 2016 Apr;55(3):1041-1057. doi: 10.1007/s00394-015-0918-x, food, 82


70. Crespo, M Carmen; Visioli, Francesco. A brief review of blue- and bilberries’ potential to curb cardio-metabolic perturbations: Focus on diabetes. Current Pharmaceutical Design. 2016 Oct Epub ahead of print


71. Visioli, F; Burgos-Ramos, E. Selected Micronutrients in Cognitive Decline Prevention and Therapy. Molecular Neurobiology. 2016 Aug;53 (6):4083-4093. doi: 10.1007/s12035-015-9349-1


72. Khymenets, O; Crespo, MC; Dangles, O; Rakotomanomana, N; Andres-Lacueva, C; Visioli, F. Human hydroxytyrosol’s absorption and excretion from a nutraceutical. Journal of Functional Foods. 2016 May;23:278-282. doi: 10.1016/j.jff.2016.02.046


73. Pela, G; Crocamo, A; Li Calzi, M; Gianfreda, M; Gioia, MI; Visioli, F; Pattoneri, P; Corradi, D; Goldoni, M; Montanari, A. Sex-related differences in left ventricular structure in early adolescent non-professional athletes. European Journal of Preventive Cardiology. 2016 May;23(7): 777-784. doi: 10.1177/2047487315608826


74. Coltell, O; Corella, D; Barragan-Arnal, R; Asensio, EM; Fernandez-Carrion, R; Portoles, O; Ferriz, E; Gonzalez, JI; Ordovas, JM; Sorli, JV. Association between the rs11614913 polymorphism in the hsa-mir-196a2 and obesity-related parameters. Cardiology. 2016;134:447-447. Suplement: 1. Abstract of meeting: 434


75. Corella, D; Sorli, JV; Frances, FG; Fernandez-Carrion, R; Estruch, R; Parnell, L; Aros, F; Saiz, C; Ordovas, JM; Coltell, O. A genetic variant in the circadian gene bmal1 is associated with higher incidence of cardiovascular diseases. Cardiology. 2016;134:245-245. Suplement: 1. Abstract of meeting: 232


76. Coltell, O; Sorli, JV; Asensio, EM; Fernandez-Carrion, R; Ortega-Azorin, C; Barragan-Arnal, R; Gonzalez-Monje, I; Aros, F; Ordovas, JM; Corella, D. A genome-wide methylation analysis shows differentially methylated regions between future cvd cases and controls. Cardiology. 2016;134: 243-243. Suplement: 1. Abstract of meeting: 230, 2016 r e p o r t, 
83


77. Lai, CQ; Wojczynski, MK; Parnell, LD; Hidalgo, BA; Irvin, MR; Aslibekyan, S; Province, MA; Absher, DM; Arnett, DK; Ordovas, JM. Epigenome-wide association study of triglyceride postprandial responses to a high-fat dietary challenge. Journal of Lipid Research. 2016 Dec;57(12):2200-2207. doi: 10.1194/jlr.M069948


78. Love-Gregory, L; Kraja, AT; Allum, F; Aslibekyan, S; Hedman, AK; Duan, Y; Borecki, IB; Arnett, DK; McCarthy, MI; Deloukas, P; Ordovas, JM; Hopkins, PN; Grundberg, E; Abumrad, NA. Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36. Journal of Lipid Research. 2016 Dec;57(12):2176-2184. doi: 10.1194/jlr.P065250


79. Malo, JE; de la Morena, ELG; Hervas, I; Mata, C; Herranz, J. Uncapped tubular poles along high-speed railway lines act as pitfall traps for cavity nesting birds. European Journal of Wildlife Research. 2016 Aug;62(4):483-489. doi: 10.1007/s10344-016-1025-x


80. Vazquez L, Gonzalez N, Reglero G, Torres C. Solvent-Free Lipase-Catalyzed Synthesis of Diacylgycerols as Low-Calorie Food Ingredients. Frontiers in Bioengineering and Biotechnology. 2016 Feb;4:6. doi:10.3389/fbioe.2016.00006


81. Hmimed S., Belarbi M., and Visioli F. Hydroxytyrosol augments the redox status of high fat diet-fed rats. PharmaNutrition. 2016 Dec;4(4):139-142. doi: 10.1016/j.phanu.2016.09.001


82. Herrera Acosta E., Alonso Suárez Pérez J.A., Aguilera Arjona, J., and Visioli F. An olive polyphenol-based nutraceutical improves cutaneous manifestations of psoriasis in humans. PharmaNutrition. 2016 Dec;4(4):151–153. doi: 10.1016/j.phanu.2016.10.002

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